The BOSS SY-300 Guitar Synthesizer requires no special pick-up. Just plug your guitar in and play. There are 70 preset patches to get going, and 99 user presets to store and create your favourite sounds. The SY-300 sounds incredible - from bright shimmering leads, to rich analog bass patches and ambient pads. The tone of the SY-300 responds to your playing, and settings on the guitar. You will notice distinct differences in a patch when changing pick-ups for example, and it can respond to pitch bends and vibrato. Modulation settings can be altered live via the foot controllers too.